教师风采

王庆志

来源:yxy发稿时间:2020-07-13浏览次数:64


 

王庆志:男,19775月生,博士研究生学历,博士学位,中西医结合基础专业,主治医师,讲师。

教学情况:近五年开设主讲的主要课程有《病理学》、《精神病学》。

科研情况:

(1)研究方向:神经退行性疾病及精神疾病的发病机制与治疗。

(2)科研课题:

主持江西省教育厅科技项目:细胞中C19orf43蛋白的功能研究;参与江西省自然科学基金项目:E3泛素连接酶gp78在帕金森病中的病理机制研究;参与国家自然科学基金项目:CDK5磷酸化Sirt2介导NLRP3炎症小体激活在帕金森氏病神经元焦亡中的机制研究。

(3)学术论文:

1. Qingzhi Wang#, Fengjuan Jiao#, Pei Zhang, Jianguo Yan, Feng He, Qian Zhang, Bo Tian*.CDK5-Mediated Phosphorylation-Dependent Ubiquitination and Degradation of E3 Ubiquitin Ligases GP78 Accelerates Neuronal Death in Parkinson's Disease. Mol Neurobiol. 2017 May 20. doi: 10.1007/s12035-017-0579-2.

2. Fengjuan Jiao#, Qingzhi Wang#, Pei Zhang, Jianguo Yan, Feng He, Qian Zhang, Bo Tian*. CDK5-mediate phosphorylation of XBP1s contributes to its nuclear translocation and activation  in MPP+-induced Parkinson's disease model. Sci Rep. 2017; 7: 5622.

3. Jianguo Yan, Pei Zhang, Fengjuan Jiao, Qingzhi Wang, Feng He, Qian Zhang, Bo Tian*. Quantitative proteomics in A30P*A53T α-synuclein transgenic mice reveals upregulation of Sel1l. PLOS One. 2017 Aug 3;12(8):e0182092.

4. Jiao F, Wang Q, Zhang P, Bu L, Yan J, Tian B*. Expression signatures of ong non-coding RNA in the substantia nigra of pre-symptomatic mouse model of Parkinson's disease. Behav Brain Res. 2017 Jul 28;331:123-130.

5. Zhang P, Wang Q, Jiao F, Yan J, Chen L, He F, Zhang Q, Tian B*. Association of LRRK2 R1628P variant with Parkinson's disease in Ethnic Han-Chinese and subgroup population. Sci Rep. 2016 Nov 4;6:35171.